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ROSUVASTATIN CALCIUM |
| Synonyms. Rosuvastatin calcium; Crestor; (3R,5S,6E)-7-(4-(4-fluorophenyl)-2-(N-methylmethane sulfonamido)- 6-(propan-2-yl) pyrimidin-5-yl)- 3,5-dihydroxyhept-6-enoic acid; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
147098-20-2 |
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EINECS RN |
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FORMULA |
2(C22H27FN3O6S).Ca;C44H54CaF2N6O12S2 |
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MOLE WEIGHT |
1001.14 |
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H.S CODE |
2932.29.5050 |
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SMILES |
CC(C1=NC(=NC(=C1/C=C/C(O)CC(O)CC(=O)[O-])C2=CC=C( C=C2) F)N(S (=O)(=O)C)C)C.CC(C1=NC(=NC(=C1/C=C/C(O)CC(O)CC(=O) [O-])C2= CC=C(C=C2)F)N(S(=O)(=O)C)C)C.[Ca+2] |
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CLASSIFICATION |
Antihyperlipidemic, HMG CoA Reductase Inhibitor, Statin, Sulfonamide |
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EXTRA NOTES |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
white to off-white crystalline powder |
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MELTING POINT |
155 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Sparingly soluble |
| SOLVENT SOLUBILITY |
Sparingly soluble in methanol. Slightly soluble in ethanol. |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Rosuvastatin calcium Wikipedia Linking - Rosuvastatin Google Scholar Search - Rosuvastatin calcium U.S. National Library of Medicine - Rosuvastatin calcium PubChem Compound Summary - Rosuvastatin calcium Drug Bank - Rosuvastatin KEGG (Kyoto Encyclopedia of Genes and Genomes) - Rosuvastatin calcium ChEBI (http://www.ebi.ac.uk/chebi/) - Rosuvastatin calcium NCBI (http://www.ncbi.nlm.nih.gov/) - Rosuvastatin calcium Hazardous Substances Data Bank - Rosuvastatin |
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| SALES SPECIFICATION | |
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APPEARANCE |
white to off-white crystalline powder |
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ASSAY |
99% min |
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MELTING POINT |
155 C |
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OPTICAL ACTIVITY |
+14.5° ~ +15.5° (c=1.012 in 50% methanol) |
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LOSS ON DRYING |
0.5% max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
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| HAZARD CLASS |
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| PACKING |
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Preserve in light-resistant and well-closed containers |
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| PRICE INFORMATION |
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